How Much Diphenhydramine Can I Take at Once

• What Is Diphenhydramine and How Does Information technology Work?
• What Are Side Effects Associated with Using Diphenhydramine?
• What Other Drugs Collaborate with Diphenhydramine?
• What Are Warnings and Precautions for Diphenhydramine?

Brand Names: Benadryl, Benadryl Allergy Dye-Free LiquiGels, Children's Benadryl Allergy, Children's Triaminic Thin Strips Allergy, Alka-Seltzer Plus Allergy, Nytol, PediaCare Children's Allergy, Simply Sleep, Sominex, QlearQuil Dark Allergy Relief, Tranquil Nighttime Slumber Aid, Unisom SleepGels, Unisom SleepMelts, ZzzQuil

Generic Name: Diphenhydramine

Drug Class: Antihistamines, 1st Generation; Antiemetic Agents

What Is Diphenhydramine and How Does It Work?

Diphenhydramine is an antihistamine which can be obtained both via a prescription and over-the-counter (OTC). Diphenhydramine tin be used to treat allergic reactions, insomnia, cough, movement sickness and Parkinsonism.

Diphenhydramine is available under the following unlike brand names: Benadryl, Benadryl Allergy Dye-Free LiquiGels, Children'south Benadryl Allergy, Children's Triaminic Sparse Strips Allergy, Alka-Seltzer Plus Allergy, Nytol, PediaCare Children's Allergy, Simply Sleep, Sominex, QlearQuil Night Allergy Relief, Tranquil Nighttime Sleep Aid, Unisom SleepGels, Unisom SleepMelts, and ZzzQuil.

Dosages of Diphenhydramine:

Oral liquid/solution

• 12.v mg/5 ml (Benadryl Allergy Childrens, PediCare Children'southward Allergy, Allergy Relief Childrens)
• 50 mg/30 ml (ZzzQuil)

Elixir

• 12.five mg/ml (Altaryl)

Syrup

• 12.5 mg/ml (Altaryl, Quenalin, Silphen Cough)

Tablet

• 25 mg (Benadryl, Nytol, Simply Sleep, Sominex, Simply Allergy, Tetra-Formula Nighttime Sleep)
• 50 mg (Aler-Dryl, Nytol Maximum Forcefulness)

Capsule

• 25 mg (Benadryl Allergy Dye-Free Allergy, Anti-Hist Allergy, Allergy Relief, Diphenhist, Geri-Dryl)
• fifty mg (Banophen, Pharbedryl)

Chewable Tablet

• 12.5 mg (Benadryl Allergy Childrens)

Dispersible Tablets

• 25 mg (Unisom SleepMelts)

Strip

• 12.5 mg (Triaminnic Coughing/Runny Nose)

Injectable solution

• 50 mg/ml

Dosage Considerations – Should exist Given as Follows:

Allergic Reaction

Developed

• 25-50 mg orally every 6-viii hours, not to exceed 300 mg/mean solar day
• 10-50 mg (no more than than 100 mg) intravenously or intramuscular every 4-half-dozen hours, not to exceed 400 mg/mean solar day

Children

• Children 2-6 years: 6.25 mg every iv-6 hours, non to exceed 37.v mg/solar day
• Children 6-12 years: 12.5-25 mg orally every 4-6 hours, not to exceed 150 mg/day
• Children 12 years and older: 25-l mg orally every 4-6 hours, not to exceed 300 mg/day

Geriatric

• 25 mg orally/intravenously/intermuscular every 8-12 hours, use only for emergency allergic reactions at smallest effective dose
• Not-anticholinergic antihistamines should be considered beginning for treatment of allergic reaction (Beers criteria); utilize of diphenhydramine in acute handling of severe allergic reaction may exist appropriate

Insomnia

Developed

• 50 mg orally 30 minutes before bedtime

Children

• Children under 12 years (off-label): 1 mg/kg; not to exceed fifty mg; 30 min before bedtime
• Children 12 years or older: 50 mg orally thirty minutes earlier bedtime

Cough

Adult

• 25-50 mg orally every 4 hours as needed (syrup preferred), not to exceed 150 mg/mean solar day

Children

• Children under 12 years: Safety and efficacy not established
• Children 12 years or older: 25-50 mg orally every 4-vi hours, not to exceed 300 mg/mean solar day

Geriatric

• 25 mg orally every 8-12 hours, avert in elderly if possible

Motility Sickness

Adult

• Treatment or as a prophylaxis: 25-fifty mg orally every half-dozen-8 hours.
• Alternatively, 10-50 mg/dose for treatment; may use upward to 100 mg if needed; non to exceed 400 mg

Children

• Administrate thirty min before movement, 12.5-25 mg orally every vi-eight hours or 150 mg/m² ; not to exceed 300 mg/24-hour interval

Geriatric

• 25 mg orally/intravenously/intramuscular every eight-12 hours

Parkinsonism

• 25 mg orally every 8 hours initially, then l mg orally every 6 hours, not to exceed 300 mg/solar day
• Alternatively, 10-50 mg intravenously at a rate not to exceed 25 mg/min; not to exceed 400 mg/day; may as well administrate 100 mg intramuscular as required

Dystonic Reaction

• 50 mg intravenously/intramuscular, may be repeated in 20-30 minutes if necessary

Geriatric Dosing Modifications

Avant-garde age is associated with reduced clearance of drug and greater adventure of confusion, dry out mouth, constipation, and other anticholinergic effects and toxicity; if used, consider lower doses.

In patients with Parkinsonism who are unable to tolerate more stiff agents, use at lowest effective dose.

QUESTION

Allergies can best be described equally: See Reply

What Are Side Furnishings Associated with Using Diphenhydramine?

Mutual side furnishings include:

• sedation
• confusion
• disrupted nerve impulses
• may decrease cognitive function in geriatric patients
• dry out rima oris
• dry nasal mucosa
• dry pharynx
• thick bronchial sputum
• low white blood jail cell count
• depression count of blood platelets
• convulsions
• elevated heart charge per unit
• low blood pressure
• nervousness
• restlessness
• blurred vision
• rapid irregular heartbeat (palpitations)
• constipation
• spinning sensation (vertigo)
• menstrual irregularities
• euphoria
• loss of appetite
• urinary retention
• inflammation of nerves
• double vision
• ringing in the ears (tinnitus)

What Other Drugs Interact with Diphenhydramine?

If your doc has directed y'all to use this medication, your doctor or pharmacist may already be aware of whatever possible drug interactions and may be monitoring you for them. Do not outset, stop, or modify the dosage of any medicine before checking with your doctor, health care provider or pharmacist kickoff.

Severe Interactions of Diphenhydramine include:

• eliglustat

Serious Interactions of Diphenhydramine include

• eluxadoline
• isocarboxazid
• mefloquine
• pramlintide
• quinidine
• sodium oxybate
• thioridazine
• tranylcypromine

Diphenhydramine has moderate interactions with at to the lowest degree 275 different drugs.

Diphenhydramine has mild interactions with at least 37 different drugs.

This document does non comprise all possible interactions. Therefore, before using this product, tell your md or pharmacist of all the products you use. Keep a list of all your medications with yous, and share the list with your md and chemist. Cheque with your physician if you have wellness questions or concerns.

SLIDESHOW

Could I Be Allergic? Detect Your Allergy Triggers Run across Slideshow

What Are Warnings and Precautions for Diphenhydramine?

Warnings

• Elderly patients: Considered high-risk medication for this historic period group because it may increase risk of falls and has high incidence of anticholinergic effects; it may exacerbate existing lower urinary tract weather or benign prostatic hyperplasia; employ in special situations may be appropriate; diphenhydramine is not recommended for treatment of insomnia, because tolerance develops and risk of anticholinergic effects increases
• This medication contains diphenhydramine. Practice non take Benadryl, Benadryl Allergy Dye-Gratis LiquiGels, Children'southward Benadryl Allergy, Children'southward Triaminic Thin Strips Allergy, Alka-Seltzer Plus Allergy, Nytol, PediaCare Children's Allergy, Only Sleep, Sominex, QlearQuil Nighttime Allergy Relief, Tranquil Nighttime Sleep Aid, Unisom SleepGels, Unisom SleepMelts, or ZzzQuil if you are allergic to diphenhydramine or any ingredients independent in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

• Documented hypersensitivity
• Lower respiratory tract affliction, such as acute asthma (controversial)
• Premature infants or neonates
• Nursing mothers
• Use every bit local anesthetic
• To make children under 6 years old sleep, when used for self-medication

Furnishings of Drug Abuse

• Patients may develop a tolerance for diphenhydramine

Short-Term Effects

• May cause primal nervous organization depression, which can impair driving or operating heavy machinery. May increment the effects of sedatives such as alcohol
• Run across "What Are Side Effects Associated with Using Diphenhydramine?"

Long-Term Furnishings

• Diphenhydramine is not recommended for treatment of insomnia in elderly patients, considering tolerance develops and hazard of anticholinergic effects increases.
• See "What Are Side Effects Associated with Using Diphenhydramine?"

Cautions

• May crusade central nervous system low, which can impair driving or operating heavy machinery
• May potentiate furnishings of sedatives such as alcohol
• Employ caution in patients with angle-closure glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstacle, and thyroid dysfunction
• Elderly patients: Considered high-chance medication for this age group because it may increase risk of falls and has high incidence of anticholinergic effects; may exacerbate existing lower urinary tract conditions or benign prostatic hyperplasia; use in special situations may be appropriate; not recommended for treatment of indisposition, because tolerance develops and gamble of anticholinergic effects increases

Pregnancy and Lactation

• Diphenhydramine use in pregnancy may be acceptable
• Either creature studies show no chance but human studies are not available, or animal studies showed pocket-sized risks and human studies were done and showed no risk
• Diphenhydramine enters into breast milk, therefore practise non utilize diphenhydramine when lactating

From

References

SOURCE:
Medscape. Diphenhydramine.
https://reference.medscape.com/drug/benadryl-nytol-diphenhydramine-343392#0

grayfaideve.blogspot.com

Source: https://www.rxlist.com/diphenhydramine/drugs-condition.htm

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